I caught the entire exchange "Live" on Cspan (I have no life). I don't know what show you were watching Sam, but that audience was definately on Franken's side. I don't remember much booing of his comments, but I do remember a lot of ill-deserved applause.
What got O'Reilly was that Franken spent most of his time at the podium calling O'Reilly a liar because, and solely because, of O'Reilly calling an award that he had gotten years ago, a Peabody I think, a Pulitzer when interviewed about Inside Edition a long time ago.
O'Reilly's point was that if that's all Franken's got to base the charge of being a liar on, he's wasting his breath. Even the other liberal on the panel said that a Peabody is a highly distinguished award to get.
What REALLY rubbed me was that Franken is one of the biggest defenders of Liberals when they get caught in major lies, and then he wants to nitpick O'Reilly for mistaking a Peabody for a Pulitzer.
What was really behind this was Franken went wayyyyyy out of his way to pi$$ O'Reilly off in order to get some publicity for his lame-a$$ book, and O'Reilly gave him exactly what he wanted.