You're going to want to wait at least 2-3 days after applying the frontline to your animal. the product works with the skin's oils and just waiting for it to dry will not keep your animal fully protected. Also, you're going to want to use it year-round, considering fleas and ticks are active during the winter months as well. I work in a veterinary clinic as a technician, and we see a LOT of lymes positive dogs every day. It's a tick-borne disease that's preventable. There's aslo a lymes vaccine, too. If you don't have cats, Advantix is another great product. It gets fleas, ticks, and mosquitoes.
Make sure to wash your hands after applying, and keep your pet away from little kids and the such for a few hours.