Vista crashes a LOT. I got it pre-installed on a new machine and it crashes on me at least once per day.
It's also not compatible with my printer/scanner combo or my digital camera software, which is a common problem. I managed to find patches to fix both hardware issues, but it doesn't work the same way and I liked the old way better.
Have you got the service packs for it? SP2 fixed pretty much everything wrong with vista