This reply isn't directed at you, Merlin. It's just something I've been thinking about here recently for all of us in this pool.
I'm not so disinclined to take changes after the Friday night at midnight deadline, but early on I was trying to avoid having massive changes across the board after that time (as well as maintaining a fair structure for making sure picks were submitted on time). A sudden "Tebow's in", or "Rodgers is out" announcement on nfl.com can and should make a difference in which pick everyone is comfortable with.
Sometimes I think Friday at midnight is too early a deadline with how teams withhold player status until the last minute, but I kinda need that deadline for me.
But to be fair, if there is a convincing reason why someone wants to make a change before the kick-off of that game, I don't see why it shouldn't be entertained. This has been a good, reliable group where my initial worries of having non-pickers each week really didn't happen. Honestly, that made this a lot easier.
So if anyone has a good reason to change a pick, put it out here or pm me with it if it's before the kick off of that game, and I'll make the change. I appreciate everyone's participation all season.