After reviewing the photos I think someone was driving south in the northbound lanes.
If not, I'm having a VERY hard time figuring out what must have happened. You can see nearly straight pavement damage marks leading from the Honda minivan southbound diagonally across the northbound lanes to the shoulder where the green SUV and white pickup came to rest.
The entire front passenger-side corner of both white vehicles is demolished. For that kind of damage, the Honda and the pickup clearly had a very high speed glancing collision. Given how far the white pickup truck travelled after the impact, it must have been moving rather quickly. But from the angles involved, I cannot imagine how the pickup had that much speed opposing the Honda unless it was travelling on the wrong side of the road.
The Google Maps view of the area where the accident occurred shows it about 1/4 mile north of the Clover Hill intersection, between a crossover and a driveway. But none of the impact damage is consistent with a crossover impact. Those are usually T-bones of at least one of the vehicles, not a high-speed glancing hit. Furthermore, the impact point is almost beyond the crossover.
I wonder if the pickup driver had a medical emergency (or was messing with a cellphone) and crossed the median at full speed.